With the need to meet mankind’s enormous and growing demand for energy—driven by a new era of industrial electrification, digital infrastructure, and the "Electrification of Everything"—while simultaneously reducing net emissions, we’re entering a Golden Age for clean energy innovation. In order to eliminate fossil fuels, recapture excess CO2, and drive decarbonization at scale, entrepreneurs working in fields like advanced nuclear, advanced materials, energy and carbon control systems, carbon capture, grid optimization, synthetic fuels, and other forms of carbon utilization are looking at taking the leap to build technology ventures dedicated to tackling specific climate challenges.
In doing so, these entrepreneurs are entering an area called “Deep Tech.” Ben Joffe at SOSV defined deep tech (also DeepTech, Hard Tech, Emerging Tech, Frontier Tech, Science Tech, Physical Tech, Future Tech, etc.) as ventures with 1. Technical risk and 2. Complexity involving the intersection of two or more disciplines, such as physics and chemistry, biology and hardware, material science and analytics, etc. (For perspective on how investors think about this space, see Joffe’s essential Deep Tech Investing 101.)
Additionally, in starting a venture, folks with PhDs in physics, chemistry, or engineering must also start learning about business, finance, and Techno-Economic Analysis (TEA) areas they may know almost nothing about. Aspiring founders must learn quickly how to form a management team, define their venture and strategy, create an entity and its corporate aesthetic, and start to pitch their idea to secure the funding that will enable them to scale from lab-scale to First-of-a-Kind (FOAK) commercial pilots. For most of these intrepid entrepreneurs who are just starting out with their first venture, doing what is needed to find funding may be the hardest part, since they have no prior experience.
Fortunately, there are a growing number of resources dedicated to educating, nurturing and funding DeepTech founders helping them navigate the business formation and ongoing funding process. We are compiling this guide to list resources available for early-stage ventures, borrowing where we can and adding new sources as they come to our attention. We hope this list will help you get the early funding you need to get your venture up and running!
One of the best resources out there is the Y Combinator Library, which reflects 15 years of learning and publishing on the art of starting a venture. Get YC’s Essential Startup Advice, Elon Musk’s guidance on how to build the future, a guide to seed fundraising, and access to fundraising templates for SAFE convertible notes, among much more.
Steve Blank, a veteran Silicon Valley entrepreneur-turned professor, hosts a combination of blog posts, books, and video lectures covering a wide range of lessons for tech entrepreneurs on his website, particularly those interested in the lean startup approach. For deep tech founders, his "customer discovery" approach is a vital tool to be used alongside your Techno-Economic Analysis (TEA).
The Deep Tech Master Skill: TEA & LCA
For ventures in advanced nuclear and hard tech, the ultimate "hack" is mastering your unit economics and environmental impact before you build. Use these resources to build a credible roadmap for investors and regulators:
Randy Komisar, a Partner Emeritus at Kleiner Perkins, is the co-author of “Straight Talk for Startups: 100 Insider Rules for Beating the Odds.” Though published in 2018, its 100 rules remain an evergreen masterclass on selecting investors, managing boards, and achieving liquidity.
Guy Kawasaki, The Art of the Start 2.0, brings two decades of original and convention-irreverent strategies, updated to help founders launch and scale in the modern tech landscape.
Matt Trevithick, a veteran venture capitalist and Co-Founder of Leitmotif Ventures, noted in a seminal panel on cold fusion that “Silicon Valley is a state of mind where entrepreneurs harbor a healthy disregard for the impossible.”
Non-dilutive funding is typically available in the form of grants or loans, which do not require the founder to give up any equity in their company. For a current and thorough breakdown of how these financing tools work, see this comprehensive guide to non-dilutive funding.
1) Department of Energy (DOE)
The DOE has shifted its primary focus from basic R&D to the rapid commercialization and deployment of "Energy Dominance" technologies.
2) The Nuclear Fast-Track: GAIN
The Gateway for Accelerated Innovation in Nuclear (GAIN) is the most critical program for nuclear founders. It provides rolling funding vouchers that allow startups to bypass the massive capital requirements of R&D by granting them direct access to the U.S. National Laboratory infrastructure and specialized technical expertise. Under the 2026 "Energy Dominance" agenda, GAIN is prioritized as the primary mechanism to move advanced fission and fusion reactors into the commercial market
Integrated R&D Grant Programs
Non-dilutive funding is valuable to any founder, deeptech or otherwise. The following three grant programs are most geared towards R&D heavy projects and ventures:
To sustain research-driven ideas, the Small Business Administration (SBA) created the Small Business Innovation Research program (SBIR). On the SBIR website, you can find relevant grants tailored to your field. The application process requires a competitive proposal including a business plan, executive summary, cost proposal, and technical proposal.
Applicants should identify the specific grant or grants that they are looking for on the Solicitations List part of the SBIR website. A “solicitation” is the specific grant opportunity. After locating the desired opportunity, applicants submit a proposal for “Phase I” funding.
If selected, you enter the three-phase program:
Winners are granted non-dilutive funding to infuse into their projects.
The SBA also manages Small Business Technology Transfer (STTR) grants, which differ from SBIR in two critical ways:
All information about SBIR and STTR grants, including specific agency programs, can be found at www.sbir.gov.
The National Science Foundation (NSF) has grants for a lot of fields that fall under the DeepTech umbrella.
All grants can be found here. The most accessible NSF funding program is called “America’s Seed Fund.” It invests up to $2.5 million in non-dilutive capital over 24+ months directly into impactful, advanced tech startups. Founders retain full ownership over the company and IP. It has very similar terms of eligibility as the SBA SBIR/STTR program, but the differences are that it is housed under the NSF, is geared towards commercially-viable startups, and has a different funding timeline. Founders submit a project pitch and will hear back in about three weeks. If accepted, they then submit a full proposal and can expect to hear back within six months. America’s Seed Fund also offers portfolio company support, mentorship, and strategy advice, as opposed to only giving grant funding. The Seed Program funds about 400 ventures per year, making over 2,500 grants between 2020 and 2025, covering 30 deeptech areas. Here you can find the portfolio of companies within the seed fund, which has seen 145+ exits and over $12 billion in private investment since 2014.
According to its website, the NSF accounts for about ¼ of federal support to academic institutions for basic research, with approximately 12,000 proposals granted out of nearly 45,000 every year. Eligibility is based on several factors; here is a comprehensive guide to proposals, awards, and procedures.
All grants open and close on their own timelines, so founders should keep track of them and complete the application process accordingly. Each grant has target dates, deadline dates, and submission windows, so make sure to apply on time!
There are grants for everyone from high schoolers to post-doctorates, and from non-profits to research institutions. Some incredibly successful companies were born from NSF grants, including Symantec, Qualcomm, and IntraLase. Many of the companies that win NSF grants go on to raise venture capital from top investors.
Established in 2011, I-Corps offers a curriculum-based, experiential learning opportunity for founders to learn about the commercialization of R&D into an independent startup. To do that, I-Corps focuses on customer discovery and translating research from a laboratory to the public marketplace.
Since its inception, the program has trained over 3,600 teams and 7,500 individuals across hundreds of universities. Out of these cohorts, there have been a total of over 1,400 startups formed, almost all fitting within DeepTech, with over $7 billion in private follow-on funding raised (and $1.7 billion in public funding) along with dozens of successful acquisitions.
I-Corps emphasizes that it is not about making a business plan or funding a scientific discovery. It is rather about “talking to customers, partners and competitors; encountering the uncertainty and excitement of creating successful innovations, [and] getting out of the university laboratory to explore the commercial potential is what the effort is about.”
I-Corps cohorts now run through 13 Regional Hubs (which have replaced the old "Nodes" system) and a network of over 100 partner universities nationwide:
To apply to I-Corps, teams must have three primary members: a technical lead, an entrepreneurial lead, and an I-Corps mentor. There are about 20-30 teams within one cohort. To apply, a team must submit an Executive Summary.
To find non-dilutive funding for deeptech ideas and ventures, always be sure to check out:
Most tech incubators offer education, network support, training, and some funding to entrepreneurs trying to launch new businesses. Not all incubators offer funding, but most provide some, and many have very fair terms that provide for minimal dilution. In the case of the very successful incubators, their dilutive funding comes with additional benefits like broader and even built-in investor networks, more press/promotion, and access to skilled advisors.
Venture Studios is a fast-growing sector, with the number of Venture Studios (VS) now exceeding 1,000. VSs have various models, but often germinate venture ideas in-house and then recruit a team and launch a startup venture around that concept. VSs usually provide all initial funding and resources to help the new venture get off the ground. The downside is that the VS owners retain a large chunk of the equity (between 20 and 40%), leaving less for the “founders,” if they can even be called that. However, in 2026, Venture Studios has solidified as a recognized asset class, particularly in deep tech, because the ventures they launch tend to grow quickly and attract intense investor interest due to their pre-vetted technical viability. For a deep dive into the different models and trade-offs, see this write-up by Max Pog.
There are a growing number of tech incubators that will provide space, funding, and mentorship to tech ventures, typically at a very early stage. All of them have different parameters for the types of ventures that they’ll work with, some requiring you to be local and some not, so research what is near you. Here is a sampling (but see the database at the end with almost 200 listings):
Please refer to the section "Venture Capitalists Doing Early-Stage Investments" below to see a list of active investors in deep tech.
Below are the key programs and competitions for deep tech and clean energy. Please note that while some dates follow an annual cycle, always check the official websites for the most current deadlines.
CalTestBed: Funded by the California Energy Commission (and administered by Next Energy Nexus, CA), this initiative provides testing vouchers (historically up to $8.8M total per cohort) for clean energy innovators to use at one of more than 60 world-class facilities. Applicants must be California-based and working on hardware with a TRL of 5-7.
Activate Fellowship: A premier two-year program that transforms technical innovators into founders. The 2026 Cohort supports "hard tech for good" across hubs in Berkeley, Boston, Houston, New York, and a virtual "Anywhere" community. Applications typically close in late October of the preceding year.
Hello Tomorrow Global Challenge: One of the longest-running deep tech competitions. The 11th edition culminates at the Hello Tomorrow Summit in Amsterdam (June 11-12, 2026), featuring an Investor Day with over 350 VCs. Applications for 2026 are closed.
TechCrunch Disrupt 2026: One of the most influential startup events in the world, taking place in San Francisco (October 27-29, 2026). The event features the Startup Battlefield 200, which provides founders with a massive platform for investor exposure and a $100,000 equity-free grand prize.
Climatebase Fellowship: A career and venture accelerator for mission-driven professionals. Cohort 9 applications close on February 23, 2026, with dedicated tracks for early-stage founders and capstone projects.
EPIC Pitch Competition: Hosted by the DOE's Energy Program for Innovation Clusters, the next major event is scheduled for March 11, 2026, in Raleigh, NC, with a prize pool exceeding $100,000.
Startup World Cup (Silicon Valley): A global pitch competition with a $1M grand prize, hosted by Pegasus Tech Ventures. The Silicon Valley regional qualifier is set for May 7, 2026, at the Computer History Museum in Mountain View. Applications close on April 26, 2026. See also other regional competitions around the globe.
H-Prize (Hydrogen Shot Incubator): A DOE-backed prize designed to accelerate affordable clean hydrogen. While the "Propose!" phase has concluded, follow-on "Prove!" phases and related DOE materials accelerators continue into 2026.
Singapore Urban Mobility Week: Replacing the older mobility challenge, this biennial event runs from November 4–6, 2026, focusing on autonomous innovation and smart infrastructure.
Deep Tech Showcase: This platform hosts monthly industry-specific events for dual-use technologies. Upcoming 2026 dates for energy and industrial founders include:
Let’s be clear: venture capital is some of the most “expensive” funding you can receive because venture capitalists require that you give up equity and share future upside in your business, in exchange for their financial and professional support. The reason that so many ventures are seeking venture capital is that, if a venture capitalist invests in you, it enhances your chances of success and validates the size of your opportunity. Venture capital funding is almost always worth the price. The problem with venture capital is that it is not available to every venture.
Here’s a list of the top Venture Capital firms most active in deep tech, most of which require a “warm” introduction. (If you wish to become an investor in one of these funds, expect to commit a million or more):
There are also hundreds of newer and less established venture capital firms looking to find great ventures around the world, many of which may also invest in deep tech. Their numbers have increased so much that folks like Saba Karim are working simply to curate lists of venture investors.
Note on VC Investment:
Each VC firm has specific investment preferences and requirements for how they go about the funding process. The best strategy is to simplify your startup as much as possible and run a dedicated process where you reach out (through warm intros) to the right investors at your target funds. Keep in mind that founders will often talk to dozens of funds before they complete a round. Remember the key distinctions about deep tech: it’s complex, it’s capital-intensive, and it’s research-heavy. Try to ease investors’ concerns here. Experienced investors in this sector understand that you won’t have the same traction as a bootstrappable app but will want to see other signs of progress.
Benjamin Joffe at SOSV has laid out common deeptech investing risks, and what investors look for: